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ddTargets (Drug Targets / Disease Target Database): This is a unique and comprehensive database on therapeutic drug targets. This database contains drug targets reported in US patents or US/International patent applications and published research articles. The drug targets are also classified according to specific drug types (e.g. small molecule drugs, protein drugs, antibody drugs, siRNA drugs, miRNA drugs etc.) and disease types. The assays and methods used for characterizing each drug targets are listed as well. All the drug targets are linked to various databases such as PubMed (articles), Google Scholar (articles), GeneBank® (nucleotide sequence), UniProt (protein sequence), USPTO (full text patents/patent applications), WO(PCT) (full text international patent applications) and Google patents (full text US patents).
Drug Targets            Drug Types            Disease Targets            New Additions

Drug Target - Beta-type platelet-derived growth factor receptor (PDGFRb)

US Patent Application: 20100081656
Patent Owner: IRM (USA)
Drug Types
Small molecule drugs
Target Diseases
Please refer to the patent or patent application for the complete list of target diseases
Acute pain, Agitation, Allergic contact dermatitis, Allergic rhinitis, Allergic sinusitis, Alzheimer's disease, Amyotrophic lateral sclerosis, Anaphylactic syndrome, Angioedema, Anorexia, Anxiety disorder, Asthma, Atopic dermatitis, Autoimmune enteropathy, Bacterial infection, Bone loss, Bone marrow fibrosis, Bulimia, Cancer, Cancer pain, Cardiac fibrosis, Cerebral ischemia, Chronic pain, Cirrhosis in liver, Conjunctivitis, Crohn's disease, Cutaneous lupus erythematosus, Cutaneous necrotizing venulitis, Cyclothymic disorder, Cystic fibrosis, Decreased libido, Depression, Dermatomyositis, Diabetes, Discoid lupus erythematosis, Drug abuse, Drug addiction, Drug dependence, Drug habituation, Dysthymic disorder, Erythema multiforme, Erythema nodosum, Fibrodysplasia ossificans progressiva, Gouty arthritis, Graft versus host disease, Hair loss, Hepatitis C infection, HIV, Huntington's chorea, Indeterminate or infectious colitis, Inflammation and tissue destruction, Inflammatory muscle disorder, Insect bite skin inflammation, Interstitial cystitis, Intestine inflammatory disease, Liver fibrosis, Local or systemic scleroderma, Loss of concentration, Macular degeneration, Mastocytosis, Mental slowing, Motor Neuron Disease, Multiple sclerosis, Nasal polyposis, Neuropathic pain, Nociceptive pain, Nodular panarteritis, Nonalcoholic steatohepatitis, Obesity, Osteoarthritis, Parkinson's disease, Pessimistic worry, Polyarthritis, Polymyositis/dermatomyositis, Post-menopause syndrome, Postoperative pain, Premenstrual syndrome, Prion diseases, Proliferative glomerulonephritis, Psoriasis, Psychogenic pain syndrome, Pulmonary fibrosis, Renal disease, Rheumatoid arthritis, Rheumatoid arthritis, Rheumatoid spondylitis, Schizophrenia, Self-deprecation, Sjogren's syndrome, Systemic lupus erythematosus, Tumor angiogenesis, Ulcerative, Urticaria, Withdrawal syndrome
Assays/Methods Used In This Patent Or Patent Application
Please refer to the patent or patent application for the complete list of methods used and the details of the protocols
  • Upstate Kinase ProfilerTM--Radio-Enzymatic Filter Binding Assay
  • Human TG-HA-VSMC Proliferation Assay
  • Effect on Cell Cycle Distribution
  • Proliferation Assay: BaF3 Library--Bright Glo Readout Protocol
  • FLT3 and PDGFR beta (Cellular Assay)
Link to USPTO site
US Patent Application: 20100081656

Drug Target - Beta-type platelet-derived growth factor receptor (PDGFRb)

US Patent Application: 20100074895
Patent Owner: Unknown
Drug Types
Small molecule drugs
Target Diseases
Please refer to the patent or patent application for the complete list of target diseases
Cancer
Assays/Methods Used In This Patent Or Patent Application
Please refer to the patent or patent application for the complete list of methods used and the details of the protocols
  • Mapping Tumor Cell Networks
  • Selecting and Stratifying Patients for Treatment
  • GLEEVEC+Vectibix Treatment
  • Therapeutics for Targeting Kinase Pathways
Link to USPTO site
US Patent Application: 20100074895
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